Aerobic Respiration - Electron Transport System

1. Electron transport system = chain of e- acceptors (embedded in the inner membrane of the mitochondrion).

2.  e- transferred from NADH + FADH2 via several e- acceptors --> final e- acceptor (molecular O2).

3.  energy produced = ATP (thru oxidative phophorylation).

4.  inhibitors = cyanide + CO - inhibit the function of ETC.
5.  Cyanide + CO --> block activity of cytochrome oxidase --> inhibit the ETS --> no production of H2O --> no activation of ATP synthase --> no ATP production.

6.  ETS:

• accepts e- from energy carriers (NADH + FADH2) from glycolysis + Krebs cycle.
• consists of mostly cytochromes (proteins with prosthetic groups).
• produces H2O from O2 at the end
• 1 NADH produces 3 ATP
• 1 FADH2 produces 2 ATP.
• net energy gain = 34 ATP molecules.