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Saturday, April 16, 2011

Aerobic Respiration - Electron Transport System

1. Electron transport system = chain of e- acceptors (embedded in the inner membrane of the mitochondrion).




















2.  e- transferred from NADH + FADH2 via several e- acceptors --> final e- acceptor (molecular O2).
3.  energy produced = ATP (thru oxidative phophorylation).
4.  inhibitors = cyanide + CO - inhibit the function of ETC.
5.  Cyanide + CO --> block activity of cytochrome oxidase --> inhibit the ETS --> no production of H2O --> no activation of ATP synthase --> no ATP production.














6.  ETS:
  • accepts e- from energy carriers (NADH + FADH2) from glycolysis + Krebs cycle.
  • consists of mostly cytochromes (proteins with prosthetic groups).
  • produces H2O from O2 at the end
  • NADH produces 3 ATP
  • FADH2 produces 2 ATP.
  • net energy gain = 34 ATP molecules.

 

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